Preparation with Eckert & Ziegler GalliaPharm Generatorġ) Connect the male luer of the outlet line of the generator to a sterile elution needle (size 21G to 23G).Ģ) Connect the Locametz vial directly to the outlet line of the generator by pushing the elution needle through the rubber septum.ģ) Elute directly from the generator into the Locametz vial.Ĥ) Perform the elution manually or by means of a pump according to the generator instructions for use.ĥ) Reconstitute the lyophilized powder with 5 mL of eluate.Ħ) At the end of the elution, disconnect the Locametz vial from the generator by removing the elution needle and the vent needle with the 0.2 micron sterile air venting filter from the rubber septum. Schematic diagrams are provided in Figures 1 and 2. Follow the generator specific procedures below. Place the Locametz vial in a lead shield container.į. Pierce the Locametz vial septum with a sterile needle connected to a 0.2 micron sterile air venting filter to maintain atmospheric pressure within the vial during the reconstitution process.Į. Flip the cap off the Locametz vial and swab the septum with an appropriate antiseptic, then allow the septum to dry.ĭ. Use suitable shielding to reduce radiation exposure.Ĭ. Prepare gallium Ga 68 gozetotide injection according to the following aseptic procedure:Ī. The instructions for use provided by the germanium-68/gallium-68 generator manufacturer should also be followed. IRE ELiT Galli Eo germanium-68/gallium-68 ( 68Ge/ 68Ga) generator.Eckert & Ziegler GalliaPharm germanium-68/gallium-68 ( 68Ge/ 68Ga) generator.Locametz allows the direct preparation of gallium Ga 68 gozetotide injection with the eluate from one of the following generators (see below for specific instruction for use with each generator): Patient PreparationĪdvise patients to be well hydrated prior to gallium Ga 68 gozetotide injection administration and to void immediately prior to and frequently during the first hours after image acquisition to reduce radiation exposure. In adults, the recommended amount of radioactivity to be administered for PET is 111 MBq to 259 MBq (3 mCi to 7 mCi) by slow intravenous injection. Radiopharmaceuticals should be used by or under the control of healthcare providers who are qualified by specific training and experience in the safe use and handling of radionuclides, and whose experience and training have been approved by the governmental agency authorized to license the use of radionuclides. Use waterproof gloves, effective radiation shielding, and other appropriate safety measures when preparing and handling gallium Ga 68 gozetotide injection. Handle the gallium Ga 68 gozetotide injection with appropriate safety measures to minimize radiation exposure. for selection of patients with metastatic prostate cancer, for whom lutetium Lu 177 vipivotide tetraxetan PSMA-directed therapy is indicated.ĭOSAGE AND ADMINISTRATION Radiation Safety – Drug HandlingĪfter reconstitution and radiolabeling of Locametz, the vial contains gallium Ga 68 gozetotide injection.with suspected recurrence based on elevated serum prostate-specific antigen (PSA) level.with suspected metastasis who are candidates for initial definitive therapy.Check the quality of your connections through speed tests and get tips on how to improve their performance.īeyond the speed tests that can be carried out, there is no doubt that the most interesting function of this tool is the possibility of carrying out a complete scan of the distribution of wifi access points, with the option of exporting them to plan the complete design of the network.Locametz, after radiolabeling with gallium-68, is indicated for positron emission tomography (PET) of prostate-specific membrane antigen (PSMA)-positive lesions in men with prostate cancer:.Analyze the access points and organize them by color-coding them according to different criteria.Detects wifi networks and analyzes their operation in real-time.The app lets you scan all rooms and produce a heat map showing where the network signal is strongest. Evaluate the quality of the signal in your home and the performance of your networks Thanks to it, you will be able to find the points where the coverage is better and place the access points you need. If you are thinking of setting up a wireless network in your home or office, there is no doubt that you need an application like NetSpot.
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